Sanofi backar efter studiebesvikelse inom MS

Franska läkemedelsjätten Sanofi faller med nästan 4 procent efter att dess experimentella läkemedel tolebrutinib inte uppnått sitt primära mål i en klinisk fas III-studie för primär progressiv multipel skleros, PPMS.

By Finwire

December 15, 2025 11:24 AM

Perseus-studien visade att läkemedlet inte fördröjde tiden till 6 månaders sammansatt bekräftad funktionsnedsättning jämfört med placebo hos PPMS-patienter, som utgör cirka 10 procent av den totala populationen med multipel skleros.

Det nedslående resultatet har fått bolaget att inte ansöka om godkännande för tolebrutinib för PPMS.

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